Dear Ed, From your description, it seems that you have a number of different medical issues that are affecting your eyesight. I sincerely believe that it will be possible to restore lost functional vision one day. If you have lost a substantial number of photoreceptor cells and now at the light perception or hand motion level, you may be able to benefit from several new sight restorative technologies that are currently being testing in human clinical trials. Currently, there are three promising technologies for sight restoration. They are: Visual Prosthetics, Optogenetics and Stem Cell photoreceptor replacement therapy. Visual prosthetic devices such as the ARGUS-2, developed by Second Sight, provides electrical stimulation of the retina to induce visual perception in blind individuals. To learn more about the ARGUS-2, please see the following weblink:
Optogenetics is an exciting new technology that is able to convert non-light sensing cells in the retina into photoreceptor-like cells. Currently, Retrosense is conducting a human clinical trial in blind patients with RP. For more information, please see the following weblink:
Stem cells hold much promise for sight restoration. However, like optogenetics, the safety and efficacy of stem cell treatments are still being evaluated in human clinical trials. ReNeuron is currently conducting a clinical trial to evaluate the safety and efficacy of a stem cell treatment to restore visual function in blind individuals with retinitis pigmentosa. For more information, please see the following weblink:
In August of last year, President Bush approved the use of federal funds to support research on a limited number of existing human embryonic stem cell lines (Bush)....
Bush banned the further funding of embryonic stem cell research.
“Even though having Parkinson’s Disease is something I’d rather not go through, I cannot find it in me to support embryonic stem cell research at this time in my life, simply because my improvement or being cured shouldn’t depend on the killing of an innocent life,” said Wilbanice Ayala, 22, of Hudson, New Hampshire....
Stem cell research can now be conducted without controversy, ..
Most HESCs are derived from embryos that were created for infertilitytreatment but that were in excess of what the infertile individual(s)ultimately needed to achieve a pregnancy. The HESCs derived from theseleftover embryos offer investigators a powerful tool for understandingthe mechanisms controlling cell differentiation. However, there arescientific and therapeutic reasons not to rely entirely on leftoverembryos. From a research standpoint, creating embryos through cloningtechnologies with cells that are known to have particular geneticmutations would allow researchers to study the underpinnings ofgenetic diseases in vitro. From a therapeutic standpoint, theHESCs obtained from leftover IVF embryos are not genetically diverseenough to address the problem of immune rejection by recipients ofstem cell transplants. (Induced pluripotent stem cells may ultimatelyprove sufficient for these research and therapeutic ends, since thecells can (a) be selected for specific genetic mutations and (b)provide an exact genetic match for stem cell recipients.) At present,the best way to address the therapeutic problem is through thecreation of a public stem cell bank that represents a geneticallydiverse pool of stem cell lines (Faden et al. 2003, Lott &Savulescu 2007). This kind of stem cell bank would require thecreation of embryos from gamete donors who share the same HLA-types(i.e., similar versions of the genes that mediate immune recognitionand rejection).
Stem Cell Research Thesis Statements
My wife has been diagnosed with RP. She is 41 and has lost 80% of her peripheral vision. Could you please put me on your mailing list for updates on your progress with Stem Cell research. This is something we would like to explore as treatment when it begins clinical trials.
Good thesis statement for stem cell research
Stem cells are extremely fascinating to what they can do they have the potential to develop into many different cell types in the body during early life and growth.