The synthesis of compounds related to khellin

Objective: The present work tackled the development and evaluation of inclusion complex of khellin (KH) and methyl-β-cyclodextrin (MβCD). In addition, it tested its possible hypoglycemic and hypolipidemic effects.

These two products are important molecules for the synthesis of new khellin derivatives .
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Vanachayangkul P, Chow N, Khan SR, Butterweck V. Prevention of renal crystal deposition by an extract of ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. Urol Res 2011;39:189-95.


The synthesis of compounds related to khellin - CORE

Khellin, Cyclodextrin complexation, Methyl-beta-cyclodextrin Hypoglycemic effect, Hypolipidemic effect
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Vanachayangkul P, Byer K, Khan S, Butterweck V. An aqueous extract of Ammi visnaga fruits and its constituents khellin and visnagin prevent cell damage caused by oxalate in renal epithelial cells. Phytomedicine 2010;17:653-8.