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Doses can range from 30mg up to 400mg. LD50 for codeine is 800mg in a averagenontolerant person. At doses of > 250mg adverse effects tend to arise, includingintense itching, flushed skin, dizziness, sedation, nausea and vomiting

Semi-Synthetic (known as opioids):

As a single product codeine is a schedule II controlled substance in the US. Whencombined with other non-controlled substance, and depending on amount per dose unit,codeine combined products range from schedule III to V.


Synthetic (also known as opioids):

Canada has OTC codeine products available if product has no more than 8 mg of codeineper unit dose. Some US areas may have codeine preps available OTC, but usually requirerelease form.


* relief of non-productive cough

oral use provides very little euphoria, mild sedation; at larger doses sedation becomesquite prominent and symptoms such as staggering and slurred speech become apparent.

Tylenol #1 w/ codeine - 8 mg codeine, 15 mg caffeine

oral use provides little euphoria so little abuse potential in that form. Wheninjected, methadone give very similar effects to morphine so has similar addictionpotential.

Tylenol #2 w/ codeine - 15 mg codeine, 15 mg caffeine

Percodan tablets are color coded according to quantity of oxycodone in each tablet, thepink have ~2.5mg and the orange and green having twice as much

Tylenol #3 w/ codeine - 30 mg codeine, 30 mg caffeine

* originally found to be useful for muscle spasms but the discovery of it's analgesicproperties has resulted in it's almost exclusive use for relief of moderate to severe pain

Tylenol #4 w/ codeine - 60 mg codeine, no caffeine

Hydromorphone is one of the most used opioids in the relief of pain for the terminallyill. The reasons being it's minimal side effects, and high potency.

note: all tablets contain same amount of acetaminophen (300 mg)

Although hydromorphone's euphoria pales with other opioids it's abuse potential comesfrom the fact the rush experienced from IV use is very similar to heroin's.

Fiorinal (aspirin, caffeine, barbital, codeine)

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