the synthesis of 4-methyl coumarin using ..

In this case the coumarin, {also named, 7-hydroxy-4-methyl-2H-benzo[b]-pyran-2-one} is not a blood thinner but is a drug used in bile therapy, .

Recently 4-methyl-7-hydroxy coumarin has been reported to have anti skin-cancer activity.

AB - 7-Fluoro-4-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-carboxylic acid has been prepared as a novel scaffold for combinatorial synthesis of coumarins. The scaffold has three points of diversity. The optimal conditions for its reactions with different nucleophiles in solid phase were obtained. Sixteen coumarin derivatives with different structures were designed and synthesized in solid phase to demonstrate its application as a scaffold for combinatorial synthesis of coumarins. Thirteen of these derivatives were obtained in high yields. Many of these model compounds fluoresce. Combinatorial libraries constructed with this novel scaffold may have interesting biological or physical properties.


Synthesis of 7-substituted 4-methyl coumarins by …

Thus resorcinol reacts with ethyl acetoacetate in boiling toluene in the presence of Nafion sheet to form the coumarin 7-hydroxy-4-methylcoumarin.

Coumarins can be synthesised by one of such methods as the Claisenrearrangement, Perkin reaction, Pechmann reaction as well as the Knoevenagelcondensation [5].


210 results found for keyword 7-hydroxy-4-methyl-coumarin

N2 - 7-Fluoro-4-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-carboxylic acid has been prepared as a novel scaffold for combinatorial synthesis of coumarins. The scaffold has three points of diversity. The optimal conditions for its reactions with different nucleophiles in solid phase were obtained. Sixteen coumarin derivatives with different structures were designed and synthesized in solid phase to demonstrate its application as a scaffold for combinatorial synthesis of coumarins. Thirteen of these derivatives were obtained in high yields. Many of these model compounds fluoresce. Combinatorial libraries constructed with this novel scaffold may have interesting biological or physical properties.

Get supplier listing of 7-Diethylamino-4-methylcoumarin ..

AB - Four new coumarins, omphalocarpin, (-)-murracarpin, murrayacarpin-A and -B together with known coumarins, scopolin, scopoletin, 5,7-dimethoxy-8-(3′-methyl-2′-oxobutyl)coumarin, (±)-murracarpin and mupanidin have been isolated from the flowers of Murraya paniculata var. omphalocarpa. Their structures have been characterized from spectral analysis, chemical transformation and/or synthesis.

4-Methyl-7-diethylamino coumarin 4-Methyl-7 ..

This paper focuses on the examination of the Photoinduced Electron Transfer (PET) and Internal Charge Transfer (ICT) for two coumarin derivatives, namely 7-methoxycoumarin-4-methyl-1-aza-18-crown-6 and di(7-methoxycoumarin-4-methyl)-1,10-diaza-18-crown-6. The spectroscopic properties were investigated by UV-Vis and fluorescence spectroscopies. It was found that a dual mechanism explains the fluorescence enhancement and blue shift in the presence of a cationic species, namely saxitoxin. The ICT was elucidated by the polarity effect of methanol on the fluorescence of di(7-methoxycoumarin-4-methyl)-1,10-diaza-18-crown-6.

Synthesis of 7-hydroxy-4-methyl coumarin, ..

7-Fluoro-4-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-carboxylic acid has been prepared as a novel scaffold for combinatorial synthesis of coumarins. The scaffold has three points of diversity. The optimal conditions for its reactions with different nucleophiles in solid phase were obtained. Sixteen coumarin derivatives with different structures were designed and synthesized in solid phase to demonstrate its application as a scaffold for combinatorial synthesis of coumarins. Thirteen of these derivatives were obtained in high yields. Many of these model compounds fluoresce. Combinatorial libraries constructed with this novel scaffold may have interesting biological or physical properties.