Iron oxide nanoparticles can be used to improve Magnetic Resonance Imaging (MRI) of cancer tumors. The nanoparticle is coated with a peptide that binds to a cancer tumor. Once the nanoparticles are attached to the tumor, the magnetic property of the.
Since the development of nanoparticles for medical applications, researchers have been in disagreement regarding the level of toxicity related to Iron Oxide Particles (IOP).
Scheme of the synthetic route to FeO@TiO core–shell nanoparticles .
Although most commercially available products using nanoparticles are found as contrast agents, recently milestones have been reached regarding anticancer therapy. The German company MagForce released their company presentation at the healthcare conference in May 2013, announcing the European Medicines Agency (EMA) approval of a new product, NanoTherm as a treatment of primary or recurrent glioblastoma multiforme, a lethal brain tumour with limited treatment options. The new treatment involves the use of an aqueous dispersion of iron oxide nanoparticles, which is injected into the tumour. Once the particles are safely transferred, an alternating magnetic field applicator is used to alternate and adjust the magnetic field strength, thus creating heat and delivering localised treatment. The particles are coated with aminosilane, and a high concentration of iron with magnetic core causes less amounts of fluid to be injected for appropriate temperature generation to be achieved.[, ] A number of contributions have been published showing pre-clinical and clinical data obtained using this platform.
Biosynthesis of Nanoparticles by Microorganisms and …
Elena Shevchenko is a scientist at the Center for Nanoscale Materials at Argonne National Laboratory. She received her first degree in chemistry at the Belorussian State University and her Ph.D. from the University of Hamburg in 2003 with Horst Weller. From 2003 to 2005 she was a joint postdoctoral fellow at Columbia University and IBM T.J. Watson Research Center. In 2005, she moved to the Molecular Foundry at Lawrence Berkeley National Laboratory as a staff scientist. Her research interests include synthesis of nanoscale materials with controllable size and shape, design of multifunctional materials through self-assembly of nanoparticles, and study of the collective properties of such materials.
and prospects of nanoparticle synthesis by ..
Oxide nanoparticles have been shown to be crucial components in numerous applications to include electronic and magnetic devices, energy storage and generation, and medical applications such as magnetic nanoparticles for use in magnetic resonance imaging (MRI). In all of these applications, particle size is critical to the utility and function of oxide nanoparticles—decreased particles size results in increased surface area, which can significantly improve the performance of the oxide nanoparticle.
magnetic iron oxide nanoparticles | Nanoparticle | Iron
Researchers at MIT have shown that iron oxide nanoparticles in water can be used to increase the amount of . The researchers believe this technique could be applied to cooling a wide range of devices, from electronics devices to fusion reactors.