m-Chlorobenzoic acid is a metabolic byproduct of the drug bupropion

Synthesis of 2,4-D 2,4-D is commonly prepared by the condensation of 2,4-dichlorophenol with monochloroacetic acid in a strongly alkaline medium at moderate temperatures (Canada, NRC, 1978; Sittig 1980; Que Hee & Sutherland, 1981), or by the chlorination of phenoxyacetic acid, but this method leads to a product with a high content of 2,4-dichlorophenol and other impurities (Melnikov, l97l).

(1973) 2,3,7,8-Tetrachlorodibenzo- p- dioxin: a potent inducer of S-aminolevulinic acid synthetase.

During 2,4-D synthesis from monochloroacetic acid and 2,4-dichlorophenol, the latter compound as well as other ortho-chlorinated by-products can give rise to a wide variety of chorinated by-products at a high temperature and high pH.


Form Supplied in: white powder, available with purity of 50%, 85%, and 98% (the rest is 3-chlorobenzoic acid and water).

(1980) Chlorophenoxy and chlorobenzoic acid herbicides; their use in eleven agricultural waterbeds and their loss to stream waters in southern Ontario, Canada, 1975-1977.