Can a scientist use federal funds to conduct research using derivatives of human embryonic stem cell lines that are not listed on the NIH Human Embryonic Stem Cell Registry?
No federal funds may be used, either by an awardee or a sub-recipient, to support research using derivatives of human embryonic stem cell lines (hESCs) that are not listed on the NIH Human Embryonic Stem Cell Registry, with the exception described below. Derivatives include, but are not limited to, subclones of hESC lines, modified hESC lines (such as a line expressing green fluorescent protein), differentiated cells developed from hESC lines (such as muscle progenitor cells), and cellular materials (such as DNA, RNA, and proteins). Thus, no federal funds may be used for the generation of new data from unapproved hESC lines or derivatives. However, publicly accessible data from unapproved lines or derivatives may be used and analyzed with federal funds.
The 2009 NIH Guidelines for Human Stem Cell Research focus primarily on pluripotent stem cells derived from human embryos. Is there NIH policy that applies to research using human fetal tissue?
Yes, there is a statute and a policy that apply to the use of human fetal tissue in NIH funded research. The governing Federal statute on human fetal tissue research and transplantation is found in sections 498A and 498B of the PHS Act, 42 U.S.C. 298g-1 and 298g-2. The statute specifically prohibits any person from knowingly acquiring, receiving, or transferring any human fetal tissue for valuable consideration, and requires certain safeguards in transplantation research. Sections 4.1.14 and 22.214.171.124 of the , detail NIH policy on research with human fetal tissue, per the statute.
Help with a Thesis statement for Embryonic Stem Cell research
May individual states pass laws to permit human embryonic stem cell research?
Yes, individual states have the authority to pass laws to permit human embryonic stem cell research using state funds.
Arguments for Embryonic Stem Cell Research - Stem …
I am an investigator using one of the human embryonic stem cell lines that I received from the NIH stem cell bank. Should I submit a "Request for Human Embryonic Stem Cell Line to be Approved for Use in NIH Funded Research"?
Unless your organization has the authority and/or rights pertaining to the human embryonic stem cell line (e.g., your organization is the owner, deriver or licensee or have written permission of the same to submit), you should not submit the request. You can see if a request has been submitted for the line you are using by checking the . (Draft requests can also be seen at .)
Proponents of embryonic stem cell research state these reasons.
Are there any restrictions on the use of lines listed on the NIH Human Embryonic Stem Cell Registry?
The "see details" link on the includes information on two categories of possible use restrictions: Provider Restrictions and NIH Restrictions. Provider Restrictions include things such as experiments that are prohibited with the cell line, or requirements that proposed research be approved by an ESCRO or other type of ethical review committee. NIH Restrictions are imposed on the use of a line based on the usage of the cells as agreed to by the donors in their informed consent process. Furthermore, other cell lines derived from a restricted hESC line are subject to the same restriction.
Embryonic stem cell research paper list - …
Those opposed to embryonic stem cell research argue that the potential benefits of such research do not justify the termination of a young human life. There is no question, they say, that even at the blastocyst stage a young human embryo is a form of human life. Therefore, opponents argue, as a human life, embryos possess the same rights and are thus entitled to the same protections as are afforded to other human beings. Dr. Jim Eckman, a member of advisory board of the Nebraska Coalition for Ethical Research (NCER), is vehemently opposed to embryonic stem cell research because he believes that it is a violation of the life, dignity, and rights of human beings: “Failure to protect embryonic and fetal human life, the most vulnerable of human beings, erodes the moral fiber of our society. An assault against any innocent human being is an assault on humanity in general. Since respect for human life is a cornerstone of civilization, human embryonic stem cell research will weaken the moral foundation of our society” (Eckman). Similar to Eckman, opponents of embryonic stem cell research believe that life begins at conception, the moment a sperm fertilizes an egg, and consequentially the destruction of a week-old human embryo is the destruction of a life. Though the majority of critical voices appreciate the effort to discover and develop cures for the benefit of suffering individuals through stem cells, they promote utilizing stem cells derived from sources other than human embryos, arguing that such research will not cause harm to another human being. Recent scientific studies have made significant progress studying stem cells obtained from adult cells and umbilical cords, neither of which involves the abortion of a human embryo.