Copper and the Synthesis of Elastin and Collagen

MD3 copper peptides are the most important component in NuGlow copper peptide skincare products. Copper is used by almost every cell in the human body to increase the natural tissue building process. The MD3 copper peptides in NuGlow copper peptide skincare products delivers copper deep within the skin’s surface, making it appear visibly fresher and firmer. Clinical studies reveal that virtually 100% of all women using ’s copper peptide skincare products, with patent pending breakthrough MD3 copper peptides technology, experience statistically significant improvement in their skin’s appearance within just four weeks.

In one small study, copper peptides stimulated collagen production in the intact skin.

Copper peptides produce a better skin renewal in combination with exfoliation or various controlled skin damage methods. Copper peptides help stimulate new capillary formation (angiogenesis), increasing the biosynthesis of collagen, elastin and the water-holding proteoglycans and glycosaminoglycans. The application of copper peptides to the skin's surface creates an environment that helps the skin tighten its barrier and increase its collagen and elastin density. The photo on the right is an ultrasound scan of the skin of a women aged 59 before treatment with the a cream containing copper peptides. On the far right is the same skin after one month of treatment with the complexes. The white-yellow colored areas are the ultrasonic reflection from skin areas that are more dense because of closer cellular binding and increased amounts of collagen and elastin. This is an effect that is opposite to the usual thinning and loosening of skin during aging.


Copper and the synthesis of elastin and collagen

In fact, copper is believed to be necessary for proper storage, use, and release of the  needed to produce hemoglobin in red blood cells.

Copper not only contributes to euphoric attraction, it can also play a part in sustaining relationships. During early stages of romantic love, the blood level of NGF (Nerve Growth Factor) nearly doubles. It was also apparent that those who reported the most intense feelings also had the highest NGF levels. But NGF then declines over a years time as passion cools. In wound models, GHK-Cu increases production of NGF.


30/05/2008 · Harris, E

AB - Dietary copper deficiency induces alterations of connective tissue metabolism that are associated with lesions in cardiovascular and other organ systems. To determine the impact of copper deficiency on characteristics of collagen in porcine myocardium and cardiac valves, weaned pigs were fed diets with adequate or deficient levels of copper. Although dietary copper did not affect the concentration of collagen in either myocardium or bicuspid valves, the degree of collagen cross-linking, as assessed by the level of hydroxylysylpyridinoline, was lower in both tissues of copper-deficient pigs. Proportions of type III collagen were increased in the left ventricle and bicuspid valves of copper-deficient pigs. Copper deficiency induced extensive remodeling, however, of the collagen fraction of cardiac interstitium. Reduction in left ventricular collagen cross-linking may provide the stimulus for the development of cardiac hypertrophy, which characterizes severe copper deficiency, by increasing the compliance of the ventricular wall. The shift in the phenotypic profile of collagen that is associated with this cardiac hypertrophy indicates synthesis of new collagen, which could affect collagen cross-linking irrespective of copper status.

THE ESSENTIALS OF COPPER - Your Body’s Protective …

ProHeal Critical Care is a medical food developed for the dietary management of wounds and conditions requiring supplemental protein. ProHeal Critical Care contains a concentrated blend of hydrolyzed collagen and whey protein for maximum protein content and absorption. ProHeal Critical Care also includes vitamin C and L-arginine to support collagen synthesis and increased blood flow to wound areas, as well as zinc and copper, cofactors in connective tissue reproduction.

blood vessels due to defective collagen

Problem 4. The biosynthesis and breakdown of collagen, elastin, and water-holding GAGs exists in a dynamic balance in young healthy skin. However after age 25, the skin's production of collagen, elastin, the water-holding GAGs is reduced while the rate of breakdown of these factors is increased and starts wrinkle formation and loss of elasticity. The problem become progressively more serious with passing years.