Despite these results, the putative mechanisms whereby marine n-3 fatty acids may modulate the carcinogenic process in some experiments were examined in another review ().
Several fatty acids, free or esterified (methyl butyrate, ethyl octanoate, dodecanoic acid...), belong to aroma compounds which are found in environmental or food systems (see the website: ).
Biosynthesis of Fatty Acids - AOCS Lipid Library
With a chain length from 2 to 6 (or 4) they are called short-chain, from 8 (or 6) to 10 they are called medium-chain and 12 up to 24 they are called long-chain fatty acids.
Biosynthesis of Saturated Fatty acids Notes
Liu Z, Jahn LA, Long W et al. (2001) Branched chain amino acids activate messenger ribonucleic acid translation regulatory proteins in human skeletal muscle, and glucocorticoids blunt this action. Journal of Clinical Endocrinology and Metabolism 86(5): 2136–2143.
BIOSYNTHESIS OF FATTY ACIDS - ТДМУ
The mostly represented fatty acids are 27:4 and 29:4n-6.
Polyenoic n-6 fatty acids with carbon chain lengths from 26 to 38 have been detected in abnormal amounts in brain of patients with the rare inherited disorder, Zellweger syndrome ().
BIOSYNTHESIS OF FATTY ACIDS - OUP Academic
They probably derived by chain elongation of shorter-chain n-6 fatty acids and accumulate because of a lack of a specific coenzyme A synthetase, the first enzyme in the beta-oxidation pathway.
An uncommon (n-6) fatty acid was discovered in retina, , acylating a NH
of very long-chain polyunsaturated fatty acid biosynthesis in ..
To date, this compound may be considered as the most unsaturated fatty acid discovered in a living structure.
The 28:7n-6 fatty acid and other very long-chain polyunsaturated fatty acids had been found in fish oil, and these had probably been derived from the diet (). The identification of 28:7n-6 in several marine dinoflagellates support that hypothesis (). That very long-chain highly unsaturated fatty acid was shown to be associated with phospholipids, and not with glycolipids ().
Several very long-chain n-6 fatty acids have been isolated from a dinoflagellate , they had 22 to 36 carbon atoms and 3 to 7 double bonds ().
The biosynthesis of polyunsaturated fatty acids in …
The question of the possibility of these plant fatty acids to be the precursors of the long-chain n-3 compounds (EPA and DHA) in transgenic plants has been examined (, ). Recent progress demonstrates the feasibility of using transgenic plants to synthesize long-cain polyunsaturated fatty acids.
The main source of n-3 fatty acids is fish oil but the market prices of that product are increasing significantly.